No he's not giving up / selling-out / otherwise retiring - at least as far as I know!!!
It is reported on the wineberserker's web-forum, that the wines of Denis have doubled in price from 2009 to 2010 vintage to an eye-watering $550 ticket for the Charmes-Chambertin (in the US!). There are reports of similar increases in other markets. I'm not sure if this is fair because many people are assuming it is the domaine that is responsible for this - I doubt it as I've seen lower prices (~150 Euros) for the 10s in Europe - that said, they are now sold out, so is this the new 'going-rate'?
Rather like Fourrier's 'top two', it does sound like I will no longer be augmenting my celler with Denis's most 'sought-after' wines though. Lucky I still have some 99s ;-)